Snipes said that there has been some talk about a Blade 4 and that he would be interested if the script was right.
Snipes didn't mention whether or not there is an actual script out there yet, or if someone is working on it, so it seems this is in the very early stages of development. The last film in the series, Blade: Trinity, written and directed by David S. Goyer, starred Snipes along with Kris Kristofferson, Jessica Biel, Dominic Purcell, Ryan Reynolds, Parker Posey, Ashley Scott and Steve Braun.
We'll be sure to keep you posted with any new developments on a new Blade film as soon as we have more information.
Blade was released August 19th, 1998 and stars Wesley Snipes, Stephen Dorff, Kris Kristofferson, N'Bushe Wright, Donal Logue, Udo Kier, Arly Jover, Traci Lords. The film is directed by Stephen Norrington.
Blade: Trinity was released December 10th, 2004 and stars Wesley Snipes, Kris Kristofferson, Dominic Purcell, Jessica Biel, Ryan Reynolds, Parker Posey, Mark Berry, John Michael Higgins. The film is directed by David S. Goyer.