Dealing with the aftermath of a newly created, crushing rift in their relationship, Sam (Jared Padalecki) and Dean (Jensen Ackles) each race down a different path to try to stop the impending apocalypse from happening. [Edit]

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The apocalypse is coming, and Sam (Jared Padalecki) and Dean (Jensen Ackles) prepare for the fight in very different ways. Sam joins Ruby (Genevieve Cortese) on a final run to kill Lilith (guest star Katherine Boecher), while Castiel (Misha Collins) and Zachariah (guest star Kurt Fuller) tell Dean it’s time to play his part in stopping Lucifer. [Edit]