"As I have already explained, the film will focus on the early days of Superman, so there will be no links with the other films. This is not a remake then. Similarly, although I still cannot talk about the script, I can assure you that this new Superman will not be based on any comic book in particular."
While Zack Snyder did mention that this new Superman reboot wouldn't be tied to the Richard Donner/Bryan Singer movies, he didn't rule out a connection to the CW's Smallville, which is ending its ten season run next spring.
The fan out cry for Tom Welling and Erica Durance to continue on in the roles of Clark Kent/Superman and Lois Lane is deafening. There is no indication that Zack Snyder is interested in either actor at this point, or that he would even consider turning Superman into a big screen version of Smallville. But he hasn't stated anything contrary to that fact, either.
Man of Steel was released June 14th, 2013 and stars Henry Cavill, Amy Adams, Michael Shannon, Diane Lane, Russell Crowe, Antje Traue, Harry Lennix, Richard Schiff. The film is directed by Zack Snyder.