Uncle Ben plays a pivotal role in Peter Parker's transformation into Spider-Man in the comic books, and in the original 2002 Spider-Man movie, where he was portrayed by Cliff Robertson.
Marc Webb is directing the movie from a script by James Vanderbilt. The Marvel Comics adaptation is expected to begin principal photography next month, so we'll likely be hearing more casting tidbits regarding the Untitled Spider-Man Reboot in the very near future.
The Amazing Spider-Man was released July 3rd, 2012 and stars Andrew Garfield, Emma Stone, Rhys Ifans, Denis Leary, Martin Sheen, Sally Field, Irrfan Khan, Campbell Scott. The film is directed by Marc Webb.