During the panel, Sony Pictures also confirmed that a CGI Lizard will be Spider-man's foe in the movie. A description from AICN describes the Lizard:
The new Lizard is massive, looking more like a cross between Venom and Killer Croc. The face has an original Ditko symmetry to it and the tongue did poke out at two frightened girls (he makes his big entrance from a girl's toilet, believe it or not). But no lab coat, naked lizard green body all bulked up and full of CGI fury."
The Amazing Spider-Man was released July 3rd, 2012 and stars Andrew Garfield, Emma Stone, Rhys Ifans, Denis Leary, Martin Sheen, Sally Field, Irrfan Khan, Campbell Scott. The film is directed by Marc Webb.