Here's what the director had to say, when asked if he was sick of people asking him about the sequel.
It seems that Seann William Scott, who co-starred in The Rundown, is likely out of this follow-up, since the director has another actor in mind for Dwayne Johnson to work with.
The original movie, which was written by James Vanderbilt (White House Down) and R.J. Stewart, followed Beck on a mission to the Amazon jungle in search of Travis (Seann William Scott), son of the mafia boss Beck is indebted to. Both Beck and Travis team up to search of lost treasure.
Oddly enough, if this project goes into production, it will be the first time Dwayne Johnson has appeared in a sequel to one of his own original movies. He has appeared in several high-profile sequels such as The Mummy Returns, Journey 2: The Mysterious Island, Fast Five, Fast & Furious 6 and G.I. Joe Retaliation without starring in any of the first films in those respective franchises.
The Rundown was released September 26th, 2003 and stars Dwayne Johnson, Seann William Scott, Rosario Dawson, Christopher Walken, Ewen Bremner, Jon Gries, William Lucking, Ernie Reyes Jr.. The film is directed by Peter Berg.