David Guggenheim wrote the screenplay on spec, which he developed with producer Simon Kinberg. Little is known about the story, although it is said to be reminiscent of Tony Scott action-dramas such as Crimson Tide and Man on Fire. The title refers to smaller submarines which drug cartels use to smuggle their product into the United States.
Tony Scott will also produce Narco Sub along with Simon Kinberg. The project is considered a priority for Fox, which has put Narco Sub on the fast track.