According to The Hollywood Reporter, Saffron Burrows, Jada Pinkett Smith and Liv Tyler are in final negotiations to join the cast of the drama Reign O'er Me for Columbia Pictures. Adam Sandler and Don Cheadle are toplining.

Helmed by Mike Binder, the film centers on a man (Sandler) who lost his family in the Sept. 11 attacks and has not recovered from his grief. He runs into his college roommate (Cheadle), who is now a psychiatrist and is determined to help him cope with the loss.

Burrows would play Donna, a patient of Cheadle's character who has entanglements with both men. Smith is set to play Janeane, the wife of Cheadle's character, while Tyler would play Angela, a psychiatrist.