Rosario Dawson and Woody Harrelson are in final negotiations to star alongside Will Smith in Columbia Pictures drama Seven Pounds, according to Variety.

The Grant Nieporte-written screenplay centers on a guilt-ridden man who inadvertently falls in love while attempting to kill himself. Dawson will play a love interest who suffers from a serious heart condition. Harrelson will portray a motel attendant who becomes intrigued by his suicidal new tenant.

The Pursuit of Happyness helmer Gabriele Muccino will direct the film.

Shooting is scheduled to begin in February for a late 2008 release.

Seven Pounds was released December 19th, 2008 and stars Will Smith, Rosario Dawson, Woody Harrelson, Michael Ealy, Barry Pepper, Elpidia Carrillo, Robinne Lee, Joe Nunez. The film is directed by Gabriele Muccino.