Majel Barrett Roddenberry, Star Trek creator Gene Roddenberry's widow who nurtured the legacy of the seminal science fiction TV series after his death, has died. She was 76. Roddenberry died of leukemia Thursday morning at her home in Bel-Air, said Sean Rossall, a family spokesman.

At Roddenberry's side were family friends and her son, Eugene Roddenberry Jr.

Roddenberry was involved in the Star Trek universe for more than four decades. She played the dark-haired Number One in the original pilot but metamorphosed into the blond, miniskirted Nurse Christine Chapel in the original 1966-69 show. She had smaller roles in all five of its television successors and many of the "Star Trek" movie incarnations, although she had little involvement in the productions.

She frequently was the voice of the ship's computer, and about two weeks ago she completed the same role for the upcoming J.J. Abrams movie Star Trek Rossall said.

Roddenberry also helped keep the franchise alive by inspiring fans and attended a major Star Trek convention each year, Rossall said.

Born Majel Lee Hudec on Feb. 23, 1932, in Cleveland, she began taking acting classes as a child. She had some stage roles, then in the late 1950s and 1960s had bit parts in a few movies and small roles in TV series, including Leave It to Beaver and Bonanza.

Star Trek was released May 8th, 2009 and stars Chris Pine, Zachary Quinto, Leonard Nimoy, Eric Bana, Bruce Greenwood, Karl Urban, Zoe Saldana, Simon Pegg. The film is directed by J.J. Abrams.