Jeremy Thomas is set to produce Annie's Box about Charles Darwin, and hiring John Collee to write and directed by Jon Amiel.

The film will be based on a biography of Darwin by Randall Keynes, the great-great grandson of the Victorian scientist. Variety notes it focuses on the period when Darwin was writing The Origin of the Species, his ground-breaking treatise on evolution, while living a family life at Down House in Kent, near London.

The 'Annie' of the title is Darwin's first daughter, whose death aged 10 left him grief-stricken. With his scientific discoveries leading him toward agnosticism, he was unable to find consolation in belief in an afterlife, but coped with his loss by plunging into his work.

Thomas plans to start production on Annie's Box next year in Down House; he's hoping for a release in 2009, the bicentennial of Darwin's birth.