New Line is in negotiations with Ben Affleck to round out the cast of ensemble comedy He's Just Not That Into You, with Drew Barrymore and Nancy Juvonen producing through their Flower Films banner, according to Variety.

Shooting starts Sept. 10 in Los Angeles, with Ken Kwapis (License to Wed) directing.

Along with Affleck and Barrymore, He's Just Not That Into You will star Jennifer Aniston, Jennifer Connelly, Kevin Connolly, Bradley Cooper, Ginnifer Goodwin, Scarlett Johansson and Justin Long.

Abby Kohn and Marc Silverstein (Never Been Kissed) adapted the bestseller about modern-day relationships which focuses on how men and women often misconstrue the intentions of the opposite sex.

He's Just Not That Into You was released February 6th, 2009 and stars Morgan Lily, Trenton Rogers, Michelle Carmichael, Jasmine Woods, Sabrina Revelle, Zoe Jarman, Alia Rhiana Eckerman, Julia Pennington. The film is directed by Ken Kwapis.