New Monsters Vs. Aliens Photo, Plus New Voice Cast!

Monsters tickets will cost more because the process adds about $15 million to a film's budget, but Katzenberg believes audiences will pay for "a premium experience."

That includes hearing Reese Witherspoon as Susan Murphy, a modern-day California girl who has the bad luck to be hit by a meteor on her wedding day and grows to be 49 feet, 11&#189 inches tall (a wink at 1958's The Attack of the 50-Foot Woman). Captured by the military, she's renamed Ginormica.

"I got very inspired when the studio showed me storyboards," says the 5-foot-2 actress. "Playing a larger-than-life woman has given me my own opportunity to make tall jokes." She also is no stranger to cinematic cheese. "My father was a fan of Roger Corman movies," she says. "I watched a lot of those on late-night TV."

Joining her giantess to fend off Rainn Wilson's evil alien Gallaxhar are Dr. Cockroach, Ph.D. (Hugh Laurie), the jellylike B.O.B. (Seth Rogen) and the half-ape, half-fish Missing Link (Will Arnett). Kiefer Sutherland speaks for Gen. W.R. Monger (get it?), and Stephen Colbert is the president.

"He plays it on steroids," Katzenberg assures.