The second season of Joss Whedon's Dollhouse will premiere Friday, Sept. 25 (9:00-10:00 PM ET/PT) on Fox. Series creator and executive producer Joss Whedon will write and direct the episode that will set the stage for Season Two.

In Dollhouse, Eliza Dushku stars as "Echo," an "Active" in a highly illegal and underground group of individuals whose personalities have been wiped clean so they can be imprinted with any number of new personas. Confined between missions to a secret facility known as the Dollhouse, the Actives are hired by the wealthy, powerful and connected to wholly become - with mind, personality and physiology - whomever the client wants or needs them to be. Whether imprinted to be a lover, an assassin, a corporate negotiator or a best friend, the Actives know no other life than the specific engagements they are in at that time - or do they?

Dollhouse is produced by 20th Century Fox Television. The series was created by Joss Whedon, who also serves as executive producer, writer and director. Tim Minear is an executive producer, while Tara Butters, Michele Fazekas and David Solomon are co-executive producers. Additionally, series star Eliza Dushku serves as a producer. The series also stars Tahmoh Penikett, Olivia Williams, Harry Lennix, Fran Kranz, Dichen Lachman and Enver Gjokaj.

An encore of the series premiere of Glee on Friday, Sept. 18 (9:00-10:00 PM ET/PT) replaces the previously announced season premiere episode of Dollhouse. The episode follows the series premiere of Brothers (8:00-8:30 PM ET/PT) and the season premiere of 'Til Death (8:30-9:00 PM ET/PT).