The Dark Knight (2008): Building Explosion #1
The building demolition/implosion/explosion happened at the old Brach's Candy Factory on the west side of Chicago. The factory, empty for several years - was dressed to look like "Gotham General Hospital" - complete with a large red cross and pharmacy sign. Demolition experts packed a four-story building with explosives and cleared the area.
"So, I was like, 'Sharlene & David are having issues with the cat,' when Carl says (BOOOM!!!) HOLY $#!T, Al QAEDA!"
From the footage online it looks like they edited the hell out of things too, before putting it on the reel.