What once was S.H.I.E.L.D. no longer exists. But their enemies are still out there. And the world can't save itself. Watch the latest Marvel's Agents of S.H.I.E.L.D. trailer as Coulson (Clark Gregg) and his team work to rebuild S.H.I.E.L.D. in Season 2 of Marvel's hit series, premiering Tuesday, September 23 at its new time, 9:00 p.m. ET on ABC! They truly are on a highway to Hell!

Coulson and his team are now wanted fugitives with limited resources--but that's not stopping them from keeping the world safe from powerful and unseen threats everywhere. However, with new members they hardly know, will S.H.I.E.L.D. ever be trusted again? Watch Marvel's Agents of S.H.I.E.L.D. on the ABC Television Network.

Marvel's Agents of S.H.I.E.L.D. stars Clark Gregg as Agent Phil Coulson, Ming-Na Wen as Agent Melinda May, Brett Dalton as Grant Ward, Chloe Bennet as Skye, Iain De Caestecker as Agent Leo Fitz, Elizabeth Henstridge as Agent Jemma Simmons and Nick Blood as Lance Hunter.

Guest starring are B.J. Britt as Agent Antoine Triplett, Nick Blood as Agent Lance Hunter, Adrian Pasdar as Brigadier General Glenn Talbot, Henry Simmons as Alphonso "Mack" Mackenzie, Patton Oswalt as Agent Billy Koenig, Lucy Lawless as Isabelle "Izzy" Hartley, Wilmer Calderon as Idaho, Reed Diamond as Daniel Whitehall, Hayley Atwell as Peggy Carter, Brian Patrick Wade as Carl Creel, Matthew Glave as Roger Browning, Simon Kassianides as Sunil Bakshi, George Stephanopoulos as self, Raquel Gardner as Carla Talbot, Ben Turner Nixon as Hydra Officer, Franco Vega as Military Leader, Rich Ceraulo as Soldier #1, and JB Tadena as Private Tilden.